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A B C D E F G H I J K L M N O P Q

Test Identifier Information

 
Registration CodeDHHV
Method

Human Herpes virus 6 - DNA detection

External Price$466.78(Exclusive of GST)
  

Specimen Collection

 
Specimen Collection Protocols

Test tube to use is EDTA(Lavender)

Patient SpecimenMin 0.5 mL CSF into sterile tube or 5 mL blood in EDTA tube
Paediatric SpecimenContact laboratory
  

Instructions for Referral to CHLabs

 
Aliquot InstructionsDo not aliquot blood.
Aliquot Transport to CHLDo not aliquot blood.
  

CHLabs Laboratory

 
DepartmentMicrobiology-Virology
Contact Details** Unknown email address **
Contact Phone Number03-3640416 / ext. 80416
Additional Information

Immunocompromised patients

HHV-6 disease in immunocompromised adults is usually due to reactivation of latent infection. HHV-6 may be an important opportunistic infection of organ transplant recipients and HIV sero-positive individuals.

 

HHV-6 is most evident as a cause of disease in BMT recipients.

 

If peripheral blood mononuclear cells are tested, distinguishing active from latent infection can be difficult. When a clinical syndrome is suggestive of HHV-6 disease, evidence of active infection can be demonstrated with a positive PCR result.

 

However, infection can commonly be present without symptoms therefore a positive PCR result does not prove that a clinical syndrome is caused by HHV-6. Detection of nucleic acid in tissue can provide stronger evidence. HHV6 has been detected in the PBMCs of healthy individuals. Therefore PCR assays on PBMCs may prove to be too sensitive and only useful for excluding current infection.

 

Primary infections

HHV-6 is recognised as a common childhood infection, which causes roseola (roseola infantum, exanthem subitum, sixth disease). Symptoms include high fever, a maculopapular rash that begins on the face or trunk, complications are rare. Often cases in children are asymptomatic with no roseola. A proportion of children present with febrile seizures.  

Primary infection in adults is not common, it presents as a mononucleosis like syndrome with lymphadenopathy, or hepatitis.

Delphic Number Test Number2746

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