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A B C D E F G H I J K L M N O P Q

Test Identifier Information

 
Registration CodeGHI
Method

Roche ICMA

Diagnostic Use / Indications

GH measurements are used during investigations of short stature, adult GH deficiency, acromegaly, gigantism and assessment of hypothalamic-pituitary function. Single GH estimates are seldom useful. If acromegaly is being considered, IGF-1 is the preferred test.

External Price$18.97(Exclusive of GST)
  

Specimen Collection

 
Pre-Testing Requirements

Patient should be unstressed and preferably fasted prior to sampling. Repeated sampling, stimulation and suppression tests are usually necessary.

It is essential to state the age of the patient and percentage above ideal body weight in order to facilitate interpretation of results.

Note: Hypothyroidism must be corrected before carrying out tests of growth hormone secretion. Other drugs, particularly progestogens, chlorpromazine, L-Dopa, etc should be avoided.

Specimen Collection Protocols

See the specific instructions for particular dynamic tests.

Note that all samples, including those in a series, must have individual unique lab ID numbers.

Patient Specimen4 ml red or purple top
Paediatric Specimen1 ml red or purple top
Sample Delivery to LabRoom temperature ASAP
  

Instructions for Referral to CHLabs

 
Aliquot Instructions>0.5 mL serum or plasma, paediatric minimum 0.25 ml
Aliquot Transport to CHLAmbient <8 hours, otherwise cold or frozen
  

CHLabs Laboratory

 
DepartmentEndocrinology Laboratory
Contact Details Email Email
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Contact Phone Number(03) 364 0885 | x80885
Test AvailabilityTwice weekly, Mon-Fri. Same day testing on request
Turnaround Time1 - 5 days
Reference Interval

GH reference range: (unstressed, no drugs):

Note: GH pulses may exceed reference values. The test is not suitable for samples obtained in pregnancy or under Pegvisomant treatment.
Adults: female   <6 µg/L
           male   <0.6 µg/L 
Children:  A response to provocative testing of <3 µg/L is indicative of GH
deficiency.  

Note: prior to 1/6/2010, reported GH values were 67% higher.

Interpretation

Raised Values - exercise, stress (physical and psychological), sleep (stage IV), protein foods, arginine, hypoglycaemia, glucagon, L-Dopa, acromegaly, gigantism, some diabetics.
Low Values - (ie impaired response to stimulation tests) hypothyroidism, hypopituitarism, obesity, prepubertal status, bromocriptine, L-Dopa, somatostatin, glucose infusion.

Uncertainty of Measurement

+/-0.03ug/L at 0.25 ug/L

12.12% at 0.25 ug/L

Additional Information

The GH method changed on June 25th 2012 from the Bioclone IRMA to the Roche ICMA. There is good agreement between GH results from these methods.

Delphic Number Test Number6539

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